Vector Labs Ab02883-23.0 Anti-CD56 [123C3], Rabbit IgG, kappa (200 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: 123C3
Synonyms: Neural cell adhesion molecule 1; NCAM1; N-CAM-1; NCAM-1
Amount: 200 μg
Application Codes Clone: IHC; WB
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody is specific for human CD56. CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system.
Application Notes: To immunophenotype proliferating cells in 21 cases with PR, immunohistochemistry was performed on human necrotic granulomatous lesions using the mouse version of this antibody. The antibody stained NK cells (Ohsawa et al, 1999; pmid:10362131). To examine hypermethylation of RASSF1A and p16 and viral infection of SV40 and MCPyV in SCLC and controls, immunohistochemistry was performed on human small cell lung cancer using the mouse version of this antibody (Helmbold et al, 2009; pmid:19473831). To study the role of CD56 in CIK-mediated cytotoxicity, western blotting was used on PMBCs with the mouse version of this antibody (Valgardsdottir et al, 2014; pmid:25201755). To create a detailed analysis of the origin, phenotype, and function of endometrial NK cells, immunohistochemistry was performed on endometrial tissues using the mouse version of this antibody (Manaster et al, 2008; pmid:18641324). To determine the morphological and immunophenotypic features of aggressive natural killer (NK) cell leukaemia, immunohistochemistry was performed on lymph nodes from aggressive natural killer (NK) cell leukaemia patients using the mouse version of this antibody (Morij et al, 2000; pmid:11012744).

Product Class:	Purified
Clone ID:	123C3
Synonyms:	Neural cell adhesion molecule 1; NCAM1; N-CAM-1; NCAM-1
Amount:	200 μg
Application Codes Clone:	IHC; WB
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement:	This antibody is specific for human CD56. CD56, is a homophilic binding glycoprotein expressed on the surface of neurons, glia and skeletal muscle. Although CD56 is often considered a marker of neural lineage commitment due to its discovery site, CD56 expression is also found in, among others, the hematopoietic system.
Application Notes:	To immunophenotype proliferating cells in 21 cases with PR, immunohistochemistry was performed on human necrotic granulomatous lesions using the mouse version of this antibody. The antibody stained NK cells (Ohsawa et al, 1999; pmid:10362131). To examine hypermethylation of RASSF1A and p16 and viral infection of SV40 and MCPyV in SCLC and controls, immunohistochemistry was performed on human small cell lung cancer using the mouse version of this antibody (Helmbold et al, 2009; pmid:19473831). To study the role of CD56 in CIK-mediated cytotoxicity, western blotting was used on PMBCs with the mouse version of this antibody (Valgardsdottir et al, 2014; pmid:25201755). To create a detailed analysis of the origin, phenotype, and function of endometrial NK cells, immunohistochemistry was performed on endometrial tissues using the mouse version of this antibody (Manaster et al, 2008; pmid:18641324). To determine the morphological and immunophenotypic features of aggressive natural killer (NK) cell leukaemia, immunohistochemistry was performed on lymph nodes from aggressive natural killer (NK) cell leukaemia patients using the mouse version of this antibody (Morij et al, 2000; pmid:11012744).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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