Mfg Part Number
Ab02887-10.0
Vector Labs Ab02887-10.0 Anti-CD23 [5E3], Human IgG1, kappa (200 μg)
Quick Overview
The mouse version of this antibody was raised by immunizing a BALB/c mouse with Daudi (human Burkitt's lymphoma cell-line).
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 5E3 |
| Synonyms: | Low affinity immunoglobulin epsilon Fc receptor; FCER2; BLAST-2; C-type lectin domain family 4 member J; Fc-epsilon-RII; Immunoglobulin E-binding factor; Lymphocyte IgE receptor |
| Amount: | 200 μg |
| Application Codes Clone: | FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody is specific for human CD23. CD23 is a low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. It has essential roles in the regulation of IgE production and in the differentiation of B-cells. |
| Application Notes: | To examine B1 and B2 cells for their ability to be rendered unresponsive by using an anti-lg tolerance protocol that is independent of receptor specificity, flow cytometry was performed on mouse splenic B cell suspensions using the mouse version of this antibody (Liou et al, 1995; pmid:7759864). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |