Mfg Part Number
Ab02902-23.0

Vector Labs Ab02902-23.0 Anti-Dynein Light Chain and recognizes rat and human homologs of both DYNLT1 and DNYLT3 [10F6-D1-D9], Rabbit IgG, kappa (200 μg)

Quick Overview
The mouse version of this antibody was raised by immunizing mice with DYNLT1- and DYNLT3-GST fusion proteins.
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Product Class:Purified
Clone ID:10F6-D1-D9
Synonyms:Dynein light chain Tctex-type 1; DYNLT1; Protein CW-1; T-complex testis-specific protein 1 homolog; Dynein light chain Tctex-type 3; DYNLT3; Protein 91/23; T-complex-associated testis-expressed 1-like
Amount:200 μg
Application Codes Clone:IP; WB; ELISA
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG1
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:This antibody is specific for DYNLT1 and DYNLT3 in both humans and rats. DYNLT1 and DYNLT3 act as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function.
Application Notes:To show the specificity of the mouse version of this antibody, immunoprecipitation and western blots on DYNLT1- and DYNLT3-GST fusion proteins were preformed with this antibody. Furthermore, the blotting and immunoprecipitating experiments were preformed on brain and tissue culture cell lysates and microtubule pellets prepared from rat brain. In both experiments it showed positive results. The antibody was isolated using ELISA on the DYNLT1- and DYNLT3-GST fusion proteins (Lo et al, 2007; pmid:17965411).
More Information
Brand Vector Labs
UNSPSC 12161500