Mfg Part Number
Ab02929-23.159
Vector Labs Ab02929-23.159 Anti-15-acetyl-deoxynivalenol [NAT-267], Rabbit IgG-Fc Fusion, (200 μg)
Quick Overview
The original antibody was generated by immunization of a llama (Llama glama) with the protein conjugate 15-DON-BSA in a TiterMax Classic adjuvant.
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| Product Class: | Purified |
|---|---|
| Clone ID: | NAT-267 |
| Synonyms: | 15-AcDON; DON; Mycotoxin; Deoxynivalenol; Vomitoxin, Fusarium mycotoxin; mNAT-267; NAT-267; ChEBI: 10022 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original VHH format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody is specific for mycotoxin 15-acetyldeoxynivalenol (15-AcDON). 15-Acetyldeoxynivalenol belongs to the class of type B trichothecene mycotoxins, generated by several Fusarium fungi. Deoxynivalenol (DON), along with 3-acetyl-deoxynivalenol (3-ADON) and 15-acetyldeoxynivalenol (15-ADON), occur in grains and cereal products and is often hazardous to humans and livestock. |
| Application Notes: | This antibody can bind 15-AcDON in a competitive direct enzyme-linked immunosorbent assay (CD-ELISA) and fluorescence polarization assay (FPA). This antibody does not cross react with DON; 3-acetyldeoxynivalenol (3-AcDON); neosolaniol (NEO); diacetoxyscirpenol (DAS); and T-2 toxin. Surface plasmon resonance (SPR) analysis of soluble NAT-267 binding kinetics to immobilized 15-DON-Horse Radish Peroxidase (HRP) indicated a dissociation constant KD of 5microM (PMID: 18632156). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |