Vector Labs Ab02931-23.0 Anti-Deoxynivalenol [3G7], Rabbit IgG, lambda (200 μg) Centrifuge Bundle Savings at Sycamore Life Sciences

Description

Product Class: Purified
Clone ID: 3G7
Synonyms: DON; Mycotoxin; Vomitoxin, Fusarium mycotoxin; ChEBI: 10022
Amount: 200 μg
Application Codes Clone: ELISA; SPR
Shipping Temperature: Wet Ice
Origin Pub PMID: 15039070
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: scFv
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody is specific for mycotoxin deoxynivalenol (DON). Deoxynivalenol belongs to the trichothecene class of mycotoxins, generated by several Fusarium fungi. Deoxynivalenol (DON), along with 3-acetyl-deoxynivalenol (3-ADON) and 15-acetyldeoxynivalenol (15-ADON), occur in grains and cereal products and is often hazardous to humans and livestock. Biochemically, deoxynivalenol is an inhibitor of protein synthesis and has hemolytic activity, causing apoptosis (cytotoxicity) and immunotoxicity to eukaryotic organisms. In animals, deoxynivalenol can cause anorexia and vomiting (PMID: 8896360; 16420629), and it can also cause human skin irritation, hemorrhaging, hematological changes, lymphocyte blastogenesis impairment, radiomimetic effects and apoptosis (PMID: 8896360; 16326049). In plants, deoxynivalenol is a virulence factor in the pathogenesis of G. zeae on wheat (PMID: 16420629).
Application Notes: This antibody is capable of binding deoxynivalenol in an ELISA and may be used for the detection of mycotoxins in contaminated food and feed samples. The biological affinity of the scFv antibody was measured by surface plasmon resonance (SPR) analysis and it was found to be significant but weaker than that of the whole anti-DON mAb (PMID: 15039070).

Product Class:	Purified
Clone ID:	3G7
Synonyms:	DON; Mycotoxin; Vomitoxin, Fusarium mycotoxin; ChEBI: 10022
Amount:	200 μg
Application Codes Clone:	ELISA; SPR
Shipping Temperature:	Wet Ice
Origin Pub PMID:	15039070
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	scFv
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format for improved compatibility with existing reagents assays and techniques.
Specificity Statement:	This antibody is specific for mycotoxin deoxynivalenol (DON). Deoxynivalenol belongs to the trichothecene class of mycotoxins, generated by several Fusarium fungi. Deoxynivalenol (DON), along with 3-acetyl-deoxynivalenol (3-ADON) and 15-acetyldeoxynivalenol (15-ADON), occur in grains and cereal products and is often hazardous to humans and livestock. Biochemically, deoxynivalenol is an inhibitor of protein synthesis and has hemolytic activity, causing apoptosis (cytotoxicity) and immunotoxicity to eukaryotic organisms. In animals, deoxynivalenol can cause anorexia and vomiting (PMID: 8896360; 16420629), and it can also cause human skin irritation, hemorrhaging, hematological changes, lymphocyte blastogenesis impairment, radiomimetic effects and apoptosis (PMID: 8896360; 16326049). In plants, deoxynivalenol is a virulence factor in the pathogenesis of G. zeae on wheat (PMID: 16420629).
Application Notes:	This antibody is capable of binding deoxynivalenol in an ELISA and may be used for the detection of mycotoxins in contaminated food and feed samples. The biological affinity of the scFv antibody was measured by surface plasmon resonance (SPR) analysis and it was found to be significant but weaker than that of the whole anti-DON mAb (PMID: 15039070).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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