Mfg Part Number
Ab02952-23.0
Vector Labs Ab02952-23.0 Anti-E-selectin [7A9], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with IL-1 activated human endothelial cells.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 7A9 |
| Synonyms: | CD62E; ELAM-1; ELAM1; Leukocyte-endothelial cell adhesion molecule 2; endothelial leukocyte adhesion molecule-1; CD62 antigen-like family member E; Leukocyte-endothelial cell adhesion molecule 2; SELE |
| Amount: | 200 μg |
| Application Codes Clone: | Blocking assay; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody recognizes the endothelial leukocyte adhesion molecule-1 (ELAM-1) protein as expressed in COS cells. |
| Application Notes: | The F(ab')2 fragment of this antibody showed dose-dependent inhibition of cells activated with IL-1 beta, cells used were human granulocytes. The antibody binds to IL-1 activated human endothelial cells (HEC) but not significantly to normal resting HEC. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |