Mfg Part Number
Ab02966-1.1
Vector Labs Ab02966-1.1 Anti-CD79b [AT105-1], Mouse IgG1, kappa (200 μg)
Quick Overview
The mouse version of this antibody was raised by immunizing a mouse with the extracellular domain of CD79B.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | AT105-1 |
| Synonyms: | B-cell antigen receptor complex-associated protein beta chain; CD79B; B-cell-specific glycoprotein B29; Ig-beta; Immunoglobulin-associated B29 protein |
| Amount: | 200 μg |
| Application Codes Clone: | WB; functional assay |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody specific for the extracellular domain of human CD79b human CD79b. CD79b is required in tandem with CD79A for initiation of the signal transduction cascade induced by the B-cell antigen receptor complex which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. |
| Application Notes: | Expression of CD79b in Raji, Daudi, and EHRB B-cell lines and the EHRB transfectant clones 9 and 12 was determined with a western blot using the mouse version of this antibody (Cragg et al, 2002; pmid:12384401). To stimulate HEK293 cells transfected with a AttBR4 site during a SHIP-1 recruitment assay the mouse version of this antibody was used. The antibody did manage to increase folding is some situations (Stopforth et al, 2018; pmid:29351998). To further our understanding of CLL biology, a western blot was performed on lysed isolated B-cells and CLL cells using the mouse version of this antibody (Johnston et al, 2018; pmid:29367434). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |