Mfg Part Number
Ab02995-23.0
Vector Labs Ab02995-23.0 Anti-p35 protein of Orthopoxvirus [1A], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was isolated from a vaccinia virus (VACV)-immune phage-display library of human single chain variable fragments (scFv) by panning against ectromelia virus (ECTV).
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| Product Class: | Purified |
|---|---|
| Clone ID: | 1A |
| Synonyms: | orthopoxvirus; vaccinia virus; cowpox virus; variola virus; ectromelia virus |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody recognizes a discontinuous epitope located on two different location of the p35 protein comprising amino acids 15-19 aa and 232-237 of the orthopoxvirus. This epitope is also present on ectromelia virus, vaccinia virus, variola virus and cowpox virus. |
| Application Notes: | This antibody is capable of recognizing ectromelia virus (ECTV), vaccinia virus (VACV) and cowpox virus (CPXV) in an ELISA. This antibody also neutralized variola virus (VARV) in a plaque reduction neutralization test. This antibody was reported to demonstrate a dose dependent inhibition of plaque formation after infection with VARV, VACV and CPXV. This antibody is also capable of recognizing a 35 kDa protein from ECTV, VARV, VACV, and CPXV and orthopoxvirus, which are encoded by the open reading frames orthologous to the ORF H3L in VACV (PMID: 29427674). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |