Mfg Part Number
Ab02998-23.0
Vector Labs Ab02998-23.0 Anti-DNA [4B1], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was derived from a 12 month old (NZB × NZW)F1 lupus mouse
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 4B1 |
| Synonyms: | ssDNA; actin; tubulin; cardiolipin; laminin. |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody is a polyspecific antibody that has binding specificity for ssDNA, actin, tubulin, cardiolipin and laminin. |
| Application Notes: | This antibody is capable of binding ssDNA, actin, tubulin, cardiolipin and to laminin in a solid phase ELISA. Indirect immunofluorescence labeling of HEp-2 cells gave a cytoplasmic staining pattern similar to that obtained with anti-cytoskeleton antibodies. Western blot analysis demonstrated that mAb 4B1 bore idiotype D23, previously shown to be characteristic of natural antibodies derived from normal mice. This antibody was able to form glomerular immune deposits (Gilbert et al., 1995; PMID: 7540257). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |