Mfg Part Number
Ab03026-3.3
Vector Labs Ab03026-3.3 Anti-S2 domain [S2A3], Mouse IgG2b, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated from a human Fab phage display library panned against the S2 subunit of the MERS-CoV spike protein (MERS-S2P).
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| Product Class: | Purified |
|---|---|
| Clone ID: | S2A3 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | MERS-S2P; MERS-CoV S2 subunit; Spike protein S2; Spike glycoprotein; S glycoprotein; E2; Peplomer protein |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IF; SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab, IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric mouse antibody was made using the variable domain sequences of the original Human Fab, IgG format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody binds specifically the S2 subunit of the MERS-CoV spike protein. It shows no cross-reactivity to spike protein of SARS-CoV. |
| Application Notes: | The specificity of this antibody (Fab) was confirmed by ELISA analysis. Immunofluorescence was performed on Vero cells using this antibody (IgG). The binding affinity of the IgG antibody towards MERS-S2P was found to be Kd= 170 pM using surface plasmon resonance. The antibody (IgG) was used as a capture antibody in sandwich ELISA (Kim et al, 2019; pmid: 31544848). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |