Mfg Part Number
Ab03037-1.1
Vector Labs Ab03037-1.1 Anti-VEGFR2 [D3-D3], Mouse IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by cloning the light chain and heavy chain variable region genes VL and VH of the anti-human VEGFR-2 antibody from the self-constructed and cultured anti-human VEGFR-2 murine monoclonal antibody mAb hybridoma cell line and using a set of designed primers to chimerically recombine mouse VL and VH with CL and CH of human IgG1.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | D3-D3 |
| Synonyms: | CD309; Vascular endothelial growth factor receptor 2; KDR; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds human VEGFR2. VEGFR2 is a tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. It plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells and promotes reorganization of the actin cytoskeleton. |
| Application Notes: | This antibody is recommended for detection of human VEGFR-2 protein through ELISA. Competitive ELISA confirmed that this antibody competes with recombinant VEGF to bind to recombinant human VEGFR-2 protein. This antibody was also used for the immunohistocemical analysis of HUVEC cells expressing VEGFR-2 protein |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |