Mfg Part Number
Ab03042-1.1
Vector Labs Ab03042-1.1 Anti-CD147 [PPAT-082-03], Mouse IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing BALB/c mice with extracellular domain of CD147-His and 50 μg / head, 100 ng / head of pertussis toxin in Freund's complete adjuvant.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | PPAT-082-03 |
| Synonyms: | Basigin; BSG; 5F7; Collagenase stimulatory factor; Extracellular matrix metalloproteinase inducer; EMMPRIN; Hepatoma-associated antigen; HAb18G; Leukocyte activation antigen M6; OK blood group antigen; Tumor cell-derived collagenase stimulatory factor; TCSF |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds human and cynomolgus monkey CD147. CD147 is a type I membrane glycoprotein and is classified into the immunoglobulin-like superfamily, and is expressed in many types of cancer. It is suggested that CD147 is also associated with cancer metastasis, invasion, and chemical drug resistance. |
| Application Notes: | The binding specificity of this antibody for human and cynomolgus monkey was determined using ELISA. This antibody was shown to interact with CD147 expressed on Raji cells and HSC-F cells in a flow cytometric analysis. This antibody was also reported to show anti-tumor effects in tumor-bearing mouse model of K562 cells, which is a chronic leukemia cell line and in tumor-bearing mouse model of SW480 cells, a colon cancer cell line. This antibody also showed CDC and ADCC activity against CD147 bearing cancerous cells (WO2017061602). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |