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Mfg Part Number

Ab03069-10.0

Vector Labs Ab03069-10.0 Anti-Glycoprotein [CK1 (BP7 10B11)], Human IgG1, kappa (200 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing mice with various antigen preparations from either of B. mallei (American Type Culture Collection [ATCC] 23344) or B. pseudomallei (ATCC 23343).

$517.40

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Description

Product Class: Purified
Clone ID: CK1 (BP7 10B11)
Synonyms: Burkholderia mallei; BM; surface glycoproteins; glanders; Burkholderia pseudomallei; BP; Burkholderia spp; melioidosis; Whitmore’s disease
Amount: 200 μg
Application Codes Clone: ELISA; WB
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody binds surface glycoprotein of Burkholderia mallei. B. mallei (BM), a host-adapted pathogen that does not normally persist in nature, causes glanders in horse. Some studies indicated that BM is highly infectious in humans by aerosol route. This antibody also cross reacts with surface glycoprotein of Burkholderia pseudomallei (BP), a causative agent of melioidosis, is a gram-negative, facultative anaerobic, motile bacillus commonly found in the soil and stagnant waters. BP infection is often due to either direct inoculation into wounds and skin abrasions or inhalation of contaminated materials. Recently, BP has been recognized as a major cause of community-acquired septicemia, resulting in significant mortality.
Application Notes: This antibody can be used for the detection of heat killed or 0.02% SDS treated samples of BP and BP using an ELISA. This antibody was reported to bind 34, 38 and 48 kDa surface glycoproteins of Burkholderia pseudomallei and 28, 38, 48 kDa surface glycoprotein of Burkholderia mallei in a western blot assay (PMID: 21573027).

Product Class:	Purified
Clone ID:	CK1 (BP7 10B11)
Synonyms:	Burkholderia mallei; BM; surface glycoproteins; glanders; Burkholderia pseudomallei; BP; Burkholderia spp; melioidosis; Whitmore’s disease
Amount:	200 μg
Application Codes Clone:	ELISA; WB
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement:	This antibody binds surface glycoprotein of Burkholderia mallei. B. mallei (BM), a host-adapted pathogen that does not normally persist in nature, causes glanders in horse. Some studies indicated that BM is highly infectious in humans by aerosol route. This antibody also cross reacts with surface glycoprotein of Burkholderia pseudomallei (BP), a causative agent of melioidosis, is a gram-negative, facultative anaerobic, motile bacillus commonly found in the soil and stagnant waters. BP infection is often due to either direct inoculation into wounds and skin abrasions or inhalation of contaminated materials. Recently, BP has been recognized as a major cause of community-acquired septicemia, resulting in significant mortality.
Application Notes:	This antibody can be used for the detection of heat killed or 0.02% SDS treated samples of BP and BP using an ELISA. This antibody was reported to bind 34, 38 and 48 kDa surface glycoproteins of Burkholderia pseudomallei and 28, 38, 48 kDa surface glycoprotein of Burkholderia mallei in a western blot assay (PMID: 21573027).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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