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Mfg Part Number

Ab03070-10.3

Vector Labs Ab03070-10.3 Anti-Capsular antigen [CK2 (BP7 2C6)], Human IgG1, Fc Silent™, kappa (200 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing mice with various antigen preparations from either of B. mallei (American Type Culture Collection [ATCC] 23344) or B. pseudomallei (ATCC 23343).

$517.40

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Description

Product Class: Purified
Clone ID: CK2 (BP7 2C6)
Heavy Chain Modification: Fc Silent™
Synonyms: surface capsule antigen; Burkholderia mallei; BM; glanders; Burkholderia pseudomallei; BP; Burkholderia spp; melioidosis; Whitmore’s disease
Amount: 200 μg
Application Codes Clone: ELISA; WB
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG2a
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody binds surface capsular antigens of Burkholderia mallei. B. mallei (BM), a host-adapted pathogen that does not normally persist in nature, causes glanders in horse. Some studies indicated that BM is highly infectious in humans by aerosol route. This antibody also cross reacts with surface capsular antigens of Burkholderia pseudomallei (BP), a causative agent of melioidosis, is a gram-negative, facultative anaerobic, motile bacillus commonly found in the soil and stagnant waters. BP infection is often due to either direct inoculation into wounds and skin abrasions or inhalation of contaminated materials. Recently, BP has been recognized as a major cause of community-acquired septicemia, resulting in significant mortality.
Application Notes: This antibody can be used for the detection of heat killed or 0.02% SDS treated samples of BP and BP using an ELISA. This antibody recognized surface-capsule antigens with molecular sizes of 38 to 52 kDa, and 200 kDa in BM and weakly reactive to 14∼28, 200 kDa antigens in BP in a western blot (PMID: 21573027).

Product Class:	Purified
Clone ID:	CK2 (BP7 2C6)
Heavy Chain Modification:	Fc Silent™
Synonyms:	surface capsule antigen; Burkholderia mallei; BM; glanders; Burkholderia pseudomallei; BP; Burkholderia spp; melioidosis; Whitmore’s disease
Amount:	200 μg
Application Codes Clone:	ELISA; WB
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG2a
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques.
Specificity Statement:	This antibody binds surface capsular antigens of Burkholderia mallei. B. mallei (BM), a host-adapted pathogen that does not normally persist in nature, causes glanders in horse. Some studies indicated that BM is highly infectious in humans by aerosol route. This antibody also cross reacts with surface capsular antigens of Burkholderia pseudomallei (BP), a causative agent of melioidosis, is a gram-negative, facultative anaerobic, motile bacillus commonly found in the soil and stagnant waters. BP infection is often due to either direct inoculation into wounds and skin abrasions or inhalation of contaminated materials. Recently, BP has been recognized as a major cause of community-acquired septicemia, resulting in significant mortality.
Application Notes:	This antibody can be used for the detection of heat killed or 0.02% SDS treated samples of BP and BP using an ELISA. This antibody recognized surface-capsule antigens with molecular sizes of 38 to 52 kDa, and 200 kDa in BM and weakly reactive to 14∼28, 200 kDa antigens in BP in a western blot (PMID: 21573027).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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