Mfg Part Number
Ab03091-10.0
Vector Labs Ab03091-10.0 Anti-Myelin basic protein [F23C6], Human IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by hyperimmunization of BALB/c mice with a synthetic peptide comprising human MBP acetyl residues 1-9.
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| Product Class: | Purified |
|---|---|
| Clone ID: | F23C6 |
| Synonyms: | MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein; F23 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human myelin basic protein (MBP), acetyl residues 1-9 (ASQKRPSQR). The MBP isoforms 4 and 14 along with PLP are most abundant protein components of the myelin membrane in the CNS. The smaller isoforms are believed to have an important role in remyelination of denuded axons in multiple sclerosis. |
| Application Notes: | This antibody can be used for the detection of human MBP in a sample using ELISA. This antibody was found to react with human MBP peptides like acetyl 1-9, 1-14, and 1-44 (PMID: 1698857). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |