Mfg Part Number
Ab03092-23.0
Vector Labs Ab03092-23.0 Anti-Myelin basic protein [845D3], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by hyperimmunization of BALB/c mice with human MBP peptide comprising amino acids from 80-89.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 845D3 |
| Synonyms: | MBP; Myelin A1 protein; Myelin membrane encephalitogenic protein; 84-5D3 |
| Amount: | 200 μg |
| Application Codes Clone: | RIA; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human myelin basic protein (MBP), amino acid residues 80-89 (QDENPVVHF). This antibody also cross reacts with bovine MBP comprising amino acids 78-88. The MBP isoforms 4 and 14 along with PLP are most abundant protein components of the myelin membrane in the CNS. The smaller isoforms are believed to have an important role in remyelination of denuded axons in multiple sclerosis. |
| Application Notes: | The epitope mapping of this antibody was done using solid phase radioimmunoassay (PMID: 2419434). This antibody can be used in the dection of MBP in a sample using ELISA (PMID: 2466871). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |