Mfg Part Number
Ab03123-10.0
Vector Labs Ab03123-10.0 Anti-PAR2 [1B5], Human IgG1, lambda (200 μg)
Quick Overview
The original antibody was generated by immunizing XenoMouse™ with PAR-2 antigen.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 1B5 |
| Synonyms: | F2RL1; PAR-2; GPR11; Proteinase-activated receptor 2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human PAR2 or proteinase-activated receptor 2 upstream to its cleavage site. PAR2 acts as a receptor for trypsin and trypsin-like enzymes coupled to G proteins. |
| Application Notes: | The initial screening of this antibody for reactivity for PAR2 was done using ELISA. The equilibrium dissociation constant (KD) of this antibody was obtained using KinExA® software and by “n-curve analysis” and it was reported that the original antibody had a KD of 3.39 nM with a 95% confidence interval of 1.36 to 5.47 nM (US8357367). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |