Mfg Part Number
Ab03132-23.0
Vector Labs Ab03132-23.0 Anti-Insulin [Ab 123 (mAb3, CC9C10)], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing female BALB/c mice with calf insulin in Freund's complete adjuvant.
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| Product Class: | Purified |
|---|---|
| Clone ID: | Ab 123 (mAb3, CC9C10) |
| Synonyms: | INS; proinsulin |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; RIA; FC |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | 2109009 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds an epitope on the B chain of calf, human and rodent insulin. Insulin is a peptide hormone produced by the beta cells of the pancreatic islets. It reduces blood glucose concentration by promoting its absorption from the blood into liver, fat and skeletal muscle cells. Decreased or absent insulin activity results in diabetes mellitus, a condition of high blood sugar level (hyperglycemia). |
| Application Notes: | This antibody can be used to detect insulin in a sample using ELISA and radioimmunoassay (PMID: 2109009; 6193965). This antibody was used in the flow cytometric analysis of insulin occupied B cell receptors in VH125SD B6 mice (PMID: 26109644). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |