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Mfg Part Number

Ab03150-23.0

Vector Labs Ab03150-23.0 Anti-p63 [60738-10D8], Rabbit IgG, kappa (200 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing 4-6 weeks old female BALB/c mice with recombinant human p63 protein having a histidine tag.

$517.40

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Description

Product Class: Purified
Clone ID: 60738-10D8
Synonyms: TP63; CUSP; Tumor protein 63; chronic ulcerative stomatitis protein; Keratinocyte transcription factor KET; Transformation-related protein 63; Tumor protein p73-like; p73L; p40; p51; 4A4
Amount: 200 μg
Application Codes Clone: ELISA; WB; IHC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody binds human p63. It acts as a sequence specific DNA binding transcriptional activator or repressor. It is also involved in notch signaling by probably inducing JAG1 and JAG2 and plays a role in the regulation of epithelial morphogenesis. The p63 molecule has a high degree of structural homology with p53 and has three similar functional domains: N-terminal transcription activation region, core DNA binding region, and C-terminal oligomerization region.
Application Notes: This antibody is highly similar to commercially available antibody 4A4 in immunohistochemical staining of p63. This antibody was used for the immunohistochemical staining of prostate cancer and breast cancer tissues. This binding specificity and affinity of this antibody was determined using ELISA. The original IgG1 antibody is reported to bind human p63 with an affinity constant of 2.47 X 10^9 M^(-1). Purified 60738-10D8 antibody can specifically detect p63 recombinant protein in western blot. (CN104447994)

Product Class:	Purified
Clone ID:	60738-10D8
Synonyms:	TP63; CUSP; Tumor protein 63; chronic ulcerative stomatitis protein; Keratinocyte transcription factor KET; Transformation-related protein 63; Tumor protein p73-like; p73L; p40; p51; 4A4
Amount:	200 μg
Application Codes Clone:	ELISA; WB; IHC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement:	This antibody binds human p63. It acts as a sequence specific DNA binding transcriptional activator or repressor. It is also involved in notch signaling by probably inducing JAG1 and JAG2 and plays a role in the regulation of epithelial morphogenesis. The p63 molecule has a high degree of structural homology with p53 and has three similar functional domains: N-terminal transcription activation region, core DNA binding region, and C-terminal oligomerization region.
Application Notes:	This antibody is highly similar to commercially available antibody 4A4 in immunohistochemical staining of p63. This antibody was used for the immunohistochemical staining of prostate cancer and breast cancer tissues. This binding specificity and affinity of this antibody was determined using ELISA. The original IgG1 antibody is reported to bind human p63 with an affinity constant of 2.47 X 10^9 M^(-1). Purified 60738-10D8 antibody can specifically detect p63 recombinant protein in western blot. (CN104447994)

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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