Mfg Part Number
Ab03157-1.29
Vector Labs Ab03157-1.29 Anti-HIV capsid protein p24 [A10F9], Mouse Fab fragment, His-Tagged, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with p24 protein.
$692.90
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| Product Class: | Purified |
|---|---|
| Clone ID: | A10F9 |
| Heavy Chain Modification: | His-Tagged |
| Synonyms: | P24; CA; Gag polyprotein |
| Amount: | 100 μg |
| Application Codes Clone: | ELISA; Crystallization; IF; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognizes a continuous epitope located at α-helix 10 (residues 196 to residues 207) in the C-terminal domain of the HIV BMJ4 p24 capsid protein. The p24 capsid protein is part of the HIV-1 Gag precursor protein (p55), together with the matrix (MA/p17) and nucleocapsid (NC/p7) protein domains. p55 is the main structural HIV-1 protein, and is uniquely responsible for virion assembly within the virus life cycle. |
| Application Notes: | The crystal structure of the Fab fragment in complex with the p24 protein from natural HIV-1 strain (BMJ4) was determined. The specificity of the antibody for the p 24 protein of BMJ4 strain was demonstrated by ELISA analysis. Immunofluorescence was performed on 293FT cells using this antibody (Gu et al., 2013; 23620741). The antibody detected CA N21C/A22C-V3 protein by Western blot analysis (Zhang et al. 2018; PMID: 30486318). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |