Mfg Part Number
Ab03177-23.0
Vector Labs Ab03177-23.0 Anti-Cytokeratin 7 [25C4], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing 4-6 weeks old female ICR mice with recombinant human cytokeratin 7 peptide in equal volume of Freund's non-complete adjuvant.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 25C4 |
| Synonyms: | CK-7; CK7; CK 7; K7; KRT7; Keratin type II cytoskeletal 7; Cytokeratin-7; Keratin-7; Sarcolectin; Type-II keratin Kb7; CGMCC NO 20776; OV-TL 12/30 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody is capable of binding human cytokeratin 7. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin 7 blocks interferon-dependent interphase and stimulates DNA synthesis in cells. It is involved in the translational regulation of the human papillomavirus type 16 E7 mRNA. |
| Application Notes: | This antibody can recognize human cytokeratin 7 in an ELISA and western blot. This antibody was used in the immunohistochemical staining paraffin frozen sections of placental trophoblasts and breast cancer tissues (CN113061184). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |