Mfg Part Number
Ab03178-1.1
Vector Labs Ab03178-1.1 Anti-Cytokeratin 8 [14C2], Mouse IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing ICR mice with a recombinant polypeptide comprising human cytokeratin 8 cross linked to bovine serum albumin and KLH carrier protein.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 14C2 |
| Synonyms: | CK8; CK-8; CK 8; KRT8; CYK8; Keratin type II cytoskeletal 8; Cytokeratin-8; Type-II keratin Kb8; CGMCC NO 20769; TS1 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG3 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG3 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human cytokeratin 8. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Together with KRT19, cytokeratin 8 helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. |
| Application Notes: | This antibody can recognize human cytokeratin 8 in an ELISA. The affinity constant for the original IgG3 antibody was calculated to be 9.6 × 10^(8) M^(-1). This antibody was used in the immunohistochemical analysis of breast cancer, liver bile duct epithelial cells and adenocarcinoma tissues (CN112940118). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |