Mfg Part Number
Ab03183-10.0
Vector Labs Ab03183-10.0 Anti-Cytokeratin 17 [A4], Human IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by panning a semisynthetic phage display library against human epidermal keratin extracted from psoriatic scales.
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| Product Class: | Purified |
|---|---|
| Clone ID: | A4 |
| Synonyms: | CK17; CK-17; KRT17; K17; Keratin; type I cytoskeletal 17; Cytokeratin-17; Keratin-17 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | Fab |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse Fab format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody is specific for human cytokeratin 17. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin 17 regulates the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). |
| Application Notes: | The binding of this antibody to human cytokeratin 17 was checked using ELISA. This antibody can be used for the identification of human cytokeratin 17 by immunohistochemistry and western blotting (PMID: 15340746). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |