Mfg Part Number
Ab03189-10.0
Vector Labs Ab03189-10.0 Anti-Cytokeratin 20 [10F6B12A9], Human IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing female ICR mice with human CK20 peptide (amino acids 411-424) conjugated to KLH in equal volume of Freund's incomplete adjuvant.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 10F6B12A9 |
| Synonyms: | CK20; CK-20; K20; KRT20; Cytokeratin-20; Keratin-20; Keratin type I cytoskeletal 20 ;Protein IT; CGMCC No 16204; Ks20.8 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; WB; IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody is specific for amino acids 411-424 of human cytokeratin 20. Cytokeratins are intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. There are 19 keratin polypeptides are found in human epithelium. Cytokeratin 20 plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, it plays a role in the secretion of mucin in the small intestine. |
| Application Notes: | This antibody can bind human cytokeratin 20 in an ELISA. It is also capable of detecting human cytokeratin 20 in a western blot assay. This antibody is similar to commercially available anti-Cytokeratin 20 antibody KS20.8 in staining various human tissues. This antibody was used in the immunohistochemical staining of paraffin sections of stomach, colon and colonic cancer tissues (CN109734805). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |