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Mfg Part Number

Ab03196-10.0

Vector Labs Ab03196-10.0 Anti-IDO1 [19C5], Human IgG1, kappa (200 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing mice with recombinant human IDO1 protein.

$517.40

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Description

Product Class: Purified
Clone ID: 19C5
Synonyms: IDO-1; IDO; INDO; Indoleamine 2 3-dioxygenase 1; Indoleamine-pyrrole 2 3-dioxygenase; CGMCC NO 20770; EPR20374
Amount: 200 μg
Application Codes Clone: ELISA; IHC
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody binds an enzyme called indoleamine 2,3-dioxygenase 1 (IDO1). This molecule catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. It is involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses. It acts as a suppressor of anti-tumor immunity. IDO1 is the target for therapy in a range of clinical settings, including cancer, chronic infections, autoimmune and allergic syndromes, and transplantation. Elevated IDO1 expression is a hallmark of major viral and bacterial infections.
Application Notes: This antibody can bind human IDO1 in an ELISA. The original mouse IgG1 antibody binds human IDO1 with an affinity constant of 7.68 X 10^(9) M^(-1). This antibody can be used for the immunohistochemical analysis of various normal and cancerous human tissues like lymph node cells and Hodgkin's lymphoma tissues. The immunohistochemical staining pattern of this antibody is similar to another anti-IDO1 antibody EPR20374 (CN113045667).

Product Class:	Purified
Clone ID:	19C5
Synonyms:	IDO-1; IDO; INDO; Indoleamine 2 3-dioxygenase 1; Indoleamine-pyrrole 2 3-dioxygenase; CGMCC NO 20770; EPR20374
Amount:	200 μg
Application Codes Clone:	ELISA; IHC
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement:	This antibody binds an enzyme called indoleamine 2,3-dioxygenase 1 (IDO1). This molecule catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway. It is involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses. It acts as a suppressor of anti-tumor immunity. IDO1 is the target for therapy in a range of clinical settings, including cancer, chronic infections, autoimmune and allergic syndromes, and transplantation. Elevated IDO1 expression is a hallmark of major viral and bacterial infections.
Application Notes:	This antibody can bind human IDO1 in an ELISA. The original mouse IgG1 antibody binds human IDO1 with an affinity constant of 7.68 X 10^(9) M^(-1). This antibody can be used for the immunohistochemical analysis of various normal and cancerous human tissues like lymph node cells and Hodgkin's lymphoma tissues. The immunohistochemical staining pattern of this antibody is similar to another anti-IDO1 antibody EPR20374 (CN113045667).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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