Mfg Part Number
Ab03206-23.0
Vector Labs Ab03206-23.0 Anti-Cadherin 17 [D2111], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing GP64 transgenic mice with human cadherin 17.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | D2111 |
| Synonyms: | Cadherin-17; CDH17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC; PET imaging |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody recognizes the human cadherin 17. Cadherins are calcium-dependent cell adhesion proteins. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Application Notes: | The binding characterization and epitope mapping of this antibody was done using ELISA. This antibody was capable of binding Huh6 cell line (liver cancer) and AGS cells (gastric cancer) in flow cytometry. Cu64 labelled version of this antibody was also used in the PET imaging of AGS transplant mice (JP2017024991). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |