Mfg Part Number
Ab03207-30.11
Vector Labs Ab03207-30.11 Anti-Cadherin 17 [AV17.3], scFv fragment (His), ScFv, (50 μg)
Quick Overview
The original antibody was isolated from a human single chain antibody fragments (scFv) library using phage display technology. The library was panned against domain 1-2 of human cadherin-17.
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| Product Class: | Purified |
|---|---|
| Clone ID: | AV17.3 |
| Heavy Chain Modification: | ScFv |
| Synonyms: | Cadherin-17; CDH17; Intestinal peptide-associated transporter HPT-1; Liver-intestine cadherin; LI-cadherin |
| Amount: | 50 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody recognizes the domain 1-2 of the human cadherin 17. This antibody also cross reacts with mouse cadherin 17. Cadherins are calcium-dependent cell adhesion proteins. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
| Application Notes: | The binding affinity of this antibody to human cadherin 17 was determined using ELISA. The scFv version of this antibody binds human and mouse cadherin-17 with an affinity of 8.43×10^(−7) M and 6.4×10^(−7) M respectively (US20190309060). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |