Mfg Part Number
Ab03215-10.3
Vector Labs Ab03215-10.3 Anti-IL-8 [928 (46G8)], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing cohorts of XMG2 XENOMOUSE® transgenic mice with recombinant human Interleukin-8 (rhIL-8).
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| Product Class: | Purified |
|---|---|
| Clone ID: | 928 (46G8) |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | IL8; Interleukin-8; CXCL8; C-X-C motif chemokine 8; Chemokine (C-X-C motif) ligand 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This reformatted human antibody was made using the variable domain sequences of the original Human IgG2 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human IL-8 and specifically recognizes an epitope containing amino acids sequence 'ELRCQCIKTYSK'. Interleukin-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. |
| Application Notes: | This antibody binds human interleukin 8 with a very high affinity of Kd = 0.06 pM. The binding characterization of this antibody was done using ELISA (PMID: 16038881; US20140105905). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |