Mfg Part Number
Ab03243-1.1
Vector Labs Ab03243-1.1 Anti-hnRNP A2/B1 [GLC82C238], Mouse IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing BALB/ mice in the abdominal cavity with human lung cancer cell line GLC82.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | GLC82C238 |
| Synonyms: | Heterogeneous nuclear ribonucleoproteins A2/B1; HNRNPA2B1; RNPA2; HNRPA2; HNRPB1; SNRPB1; HNRNPA2; HNRNPB1; IBMPFD2; HNRPA2B1 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds human heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNPA2/B1 is expressed during proliferation and metastasis of various cancer types and promotes such processes. |
| Application Notes: | This antibody was used in the immunohistochemical analysis of hnRNP A2/B1 expressed in lung squamous cell carcinoma, alveolar cancer and lung adenocarcinoma tissues. The binding of this antibody to HnRNP A2/B1 antigen was confirmed using western blotting (CN1273489). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |