Mfg Part Number
Ab03258-23.0
Vector Labs Ab03258-23.0 Anti-Ciguatoxin CTX3C [10C9], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing mice with a synthetic hapten comprising ABCDE ring portion conjugated with KLH.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 10C9 |
| Synonyms: | CTX; CTX3C; 51-hydroxy-CTX3C |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; neutralize |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody specifically recognizes the ABCDE ring portion of ciguatoxin CTX3C and 51-OH-CTX3C. This antibody does not cross react with other toxins like brevetoxin A (BTX-A), brevetoxin B (BTX-B), okadaic acid (OA), and maitotoxin (MTX). Ciguatoxins are the major causative toxins of ciguatera seafood poisoning (CFP). Ciguatera is a foodborne illness caused by eating reef fish whose flesh is contaminated with ciguatoxins. |
| Application Notes: | This antibody can be used to detect ciguatoxins in a sample using ELISA. It was also used in the development of a sandwich ELISA to detect CTX3C at the ppb level. Dissociation constant of this antibody for ciguatoxin CTX3C was Kd = 2.8 nM (PMID: 12812503). This antibody was also used in combination with another antibody 3D11 for effective neutralization of ciguatoxins in vitro and in vivo (PMID: 19254735). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |