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Mfg Part Number

Ab03276-10.3

Vector Labs Ab03276-10.3 Anti-Alpha Dystroglycan [1G12], Human IgG1, Fc Silent™, kappa (200 μg)

VECTOR LABS

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Quick Overview

The original antibody was generated by immunizing BALB/c mice with recombinant human α-distroglycan.

$517.40

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Description

Product Class: Purified
Clone ID: 1G12
Heavy Chain Modification: Fc Silent™
Synonyms: Dystroglycan 1; Dag1; αDG; Alpha-DG; α-DAG; ALPHA DAG; Dystroglycan; Dystrophin-associated glycoprotein 1; A-Dystroglycan; A Dystroglycan; Alpha-dystroglycan; α dystroglycan; α-dystroglycan; 2-1G12-1-26
Amount: 200 μg
Application Codes Clone: ELISA; WB; FC; IF
Shipping Temperature: Wet Ice
Buffer Composition: PBS with 0.02% Proclin 300.
Original Format: IgG1
Storage Temperature: Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement: This antibody specifically binds glycerol phosphate modifying group of human alpha dystroglycan. Alpha-dystroglycan (αDG) is an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains, and for certain adenoviruses. It is also a receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells and a receptor for laminin LAMA5. Defective glycosylation of alpha-dystroglycan is a biological marker for muscular dystrophy-dystroglycanopathy type A (MDDGA1), Walker-Warburg syndrome (WWS), muscle-eye-brain disease (MEB) and Fushan congenital muscle malnutrition (FCMD).
Application Notes: The binding characterization of this antibody towards glycerol phosphate modifying group of alpha dystroglycan was done using ELISA. This antibody can recognize glycerol phosphate modifying group of alpha dystroglycan in an western blot and flow cytometric assay. This antibody can also be used for the immunofluorescence staining of colon cancer tissue (JP2022060048).

Product Class:	Purified
Clone ID:	1G12
Heavy Chain Modification:	Fc Silent™
Synonyms:	Dystroglycan 1; Dag1; αDG; Alpha-DG; α-DAG; ALPHA DAG; Dystroglycan; Dystrophin-associated glycoprotein 1; A-Dystroglycan; A Dystroglycan; Alpha-dystroglycan; α dystroglycan; α-dystroglycan; 2-1G12-1-26
Amount:	200 μg
Application Codes Clone:	ELISA; WB; FC; IF
Shipping Temperature:	Wet Ice
Buffer Composition:	PBS with 0.02% Proclin 300.
Original Format:	IgG1
Storage Temperature:	Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:	This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.
Specificity Statement:	This antibody specifically binds glycerol phosphate modifying group of human alpha dystroglycan. Alpha-dystroglycan (αDG) is an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains, and for certain adenoviruses. It is also a receptor for laminin-2 (LAMA2) and agrin in peripheral nerve Schwann cells and a receptor for laminin LAMA5. Defective glycosylation of alpha-dystroglycan is a biological marker for muscular dystrophy-dystroglycanopathy type A (MDDGA1), Walker-Warburg syndrome (WWS), muscle-eye-brain disease (MEB) and Fushan congenital muscle malnutrition (FCMD).
Application Notes:	The binding characterization of this antibody towards glycerol phosphate modifying group of alpha dystroglycan was done using ELISA. This antibody can recognize glycerol phosphate modifying group of alpha dystroglycan in an western blot and flow cytometric assay. This antibody can also be used for the immunofluorescence staining of colon cancer tissue (JP2022060048).

Specifications

More Information
Brand	Vector Labs
UNSPSC	12161500

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