Mfg Part Number
Ab03289-23.159-BS
Vector Labs Ab03289-23.159-BS Anti-Methotrexate [R3.04], Rabbit IgG-Fc Fusion, (5 mg)
Quick Overview
The original antibody was generated by immunizing a female llama with methotrexate–BIP conjugate.
$7,342.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | R3.04 |
| Synonyms: | MTX; amethopterin; 4-amino-N10-methylpteroylglutamic acid; 4-amino-10-methylfolic acid; CHEBI:44185; CAS number: 59-05-2 |
| Amount: | 5 mg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS only. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds methotrexate, formerly known as amethopterin. It is a chemotherapy agent and immune-system suppressant. It is often used in treatment of cancer, autoimmune diseases, ectopic pregnancy and for medical abortions. |
| Application Notes: | The binding reactivity of this single chain antibody for methotrexate-BSA was done using direct and competitive ELISA, with no cross reactivity with only BSA. The binding affinity of the original VHH version of this antibody as determined by BIAcore analysis was reported to be Kd=29 nM (PMID: 17011035). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |