Mfg Part Number
Ab03299-1.1
Vector Labs Ab03299-1.1 Anti-dioxin [DD1], Mouse IgG1, kappa (200 μg)
Quick Overview
The antibody was generated by immunizing Biozzi mice with 1-N-(adipamino)-2,3,7-triCDD-linked carrier-protein BSA.
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| Product Class: | Purified |
|---|---|
| Clone ID: | DD1 |
| Synonyms: | PCDD; DLCs; PCDF; TCDD; DD-1 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Origin Pub PMID: | PMID: 7959026 |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | The antibody recognizes tetrachloro- and pentachloro-dibenzodioxins and -dibenzofurans. It falls to bind either non-chlorinated, mono-, hexa-, or octa-chlorinated dibenzodioxins, nor does it recognize non-chlorinated, octachloro- or 1,2,3,4,8,9-hexachlorodibenzofurans. Dioxins are a group of chemical compounds that are persistent organic pollutants (POPs) in the environment. |
| Application Notes: | The specificity of the antibody for 2,3,7,8-TCDD was confirmed by ELISA analysis. In order to evaluate the ability of the antibody to recognize various kinds of polychlorinated dibenzodioxins and dibenzofurans, a competition ELISA was developed. The antibody recognized 3,3',4,4'-PCB and the single-ring, chlorinated compounds, 2,4,5-trichlorophenol, mixed isomers of hexachlorocyclohexane and 2,5-dinitrobenzene. The antibody is suitable for the development of rapid, inexpensive screening assays for monitoring the presence of dioxin in biological, soil and other environmental samples (Stanker et al., 1987; PMID: 3629609).Further, the recombinant Fab antibody was generated; it displayed competitive inhibition with 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD) in an indirect ELISA (Lee et al.; 1998). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |