Mfg Part Number
Ab03312-10.0
Vector Labs Ab03312-10.0 Anti-Calponin protein [24H5], Human IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing mice with Calponin protein.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 24H5 |
| Synonyms: | CAP; Calponin-2; Calponin H2, smooth muscle; Neutral calponin; CGMCNO 20775 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2b |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for calponin protein. Calponin protein is a thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. Further, the interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. |
| Application Notes: | The antibody specifically detected Calponin beta protein in Western blot analysis. The antibody 24H5 and the commercial antibody CALP were used to stain uterine fibroids and liver tissue. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 24H5 was higher than the commercial antibody (CN113234155A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |