Mfg Part Number
Ab03314-23.0
Vector Labs Ab03314-23.0 Anti-LAG-3 [22G3], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing mice with recombinant LAG3 protein.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 22G3 |
| Synonyms: | CD223; LAG3; Lymphocyte-activation gene-3; Lymphocyte activation gene 3 protein; LAG-3; CGMCNO 20774 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for LAG3. Lymphocyte activation gene 3 protein is an inhibitory receptor on antigen activated T-cells. It delivers inhibitory signals upon binding to ligands, such as FGL1. |
| Application Notes: | The antibody specifically detected LAG3 protein in Western blot analysis. The antibody and the commercial antibody EPR20261 were used to stain tonsillar granulocytes and granulocytes in the appendix. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 22G3 was higher than the commercial antibody. The antibody and the commercially available antibody E3 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113234159A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |