Mfg Part Number
Ab03318-10.3
Vector Labs Ab03318-10.3 Anti-Progesterone Receptor [14B3], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing rabbits with PR protein.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 14B3 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | PR; Nuclear receptor subfamily 3 group C member 3 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Rabbit IgG format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for PR protein. PR is a protein molecule, a cellular core receptor belonging to a steroidal superfamily, which can be bonded to the corresponding hormone to form a hormone-receptor complex, enabling hormones to exert their biological effects. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis (affinity constant of 1.82 × 10^10 M-1). The antibody specifically detected PR protein in Western blot analysis. The antibody 14B3 and the commercial antibody 1E2 were used to stain breast cancer and endometrial. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 14B3 was higher than the commercial antibody (CN113583132A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |