Mfg Part Number
Ab03337-10.3
Vector Labs Ab03337-10.3 Anti-Cytokeratin 10 [RKSE60], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing a BALB/c mouse with Cytokeratins from the Human epidermis.
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| Product Class: | Purified |
|---|---|
| Clone ID: | RKSE60 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | K10; CK-10; Keratin K10; Keratin type I cytoskeletal 10; Cytokeratin-10; Keratin-10 |
| Amount: | 100 μg |
| Application Codes Clone: | FC; IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The original antibody reacts exclusively with Cytokeratin 10 which is present in Keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas. |
| Application Notes: | The original antibody specifically reacted with keratinizing stratified epithelia and squamous cell carcinomas derived from these by IHC (Ramaekers et al. 1983; PMID: 6350235). The antibody stained cytokeratin 10 from cultured human keratinocytes by immunohistochemistry (Muijen et al, 1987; PMID: 2442018). This antibody was used for detection of cytokeratin 10 in psoriatic skin and normal skin by flow cytometry (van Erp et al., 1989; PMID: 2479273). The antibody detected cytokeratin 10 from human foreskin keratin preparation, by western blot analysis (Ramaekers et al., 1990; PMID: 1690512). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |