Mfg Part Number
Ab03340-10.0
Vector Labs Ab03340-10.0 Anti-Cytokeratin 18 [RCK106], Human IgG1, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing a mouse with cytokeratins from the Human bladder carcinoma cell line T24.
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| Product Class: | Purified |
|---|---|
| Clone ID: | RCK106 |
| Synonyms: | K18; CK-18; Keratin K18; Keratin type I cytoskeletal 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; Keratin-18 |
| Amount: | 100 μg |
| Application Codes Clone: | FC; IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody reacts exclusively with Cytokeratin 18 in glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells, as well as adenocarcinomas originating from them. |
| Application Notes: | The antibody detected Cytokeratin 18 by western blot analysis. The antibody reacted with endocervical columnar cells, cervical immature squamous metaplasia and CINIII by immunohistochemistry (Smedts et al., 1990; PMID: 1690513). The antibody stained transitional cell carcinomas of the urinary tract of different grade and stage (Schaafsma et al., 1990; PMID: 1689541). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |