Mfg Part Number
Ab03341-10.3
Vector Labs Ab03341-10.3 Anti-Cytokeratin 19 [RCK108], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing mice with cell line T24.
$570.70
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| Product Class: | Purified |
|---|---|
| Clone ID: | RCK108 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | K19; CK-19; Keratin type I cytoskeletal 19; Cytokeratin-19; Keratin-19 |
| Amount: | 100 μg |
| Application Codes Clone: | IHC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for Cytokeratin 19. Cytokeratin 19 is found in most simple epithelia and non keratinized squamous epithelia with predominant focal reactivity. |
| Application Notes: | The antibody could be used as a broad epithelial marker for carcinoma detection, due to its reproducible and highly sensitive staining. The antibody stained practically all epithelial tumours, especially adenocarcinoma, but it is negative in hepatocellular carcinoma (Kwaspen et al., 1997; PMID: 9447381). Antibody RCK108 reacts with a 40 kDa keratin (Cytokeratin 19) in immunoblot. |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |