Mfg Part Number
Ab03354-10.3
Vector Labs Ab03354-10.3 Anti-Reticulon-1C [RNL-4], Human IgG1, Fc Silent™, kappa (100 μg)
Quick Overview
The original antibody was generated by immunizing a BALB/c mouse with a synthetic peptide encompassing the unique 20 N-terminal amino acid sequence of Reticulon-1C.
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| Product Class: | Purified |
|---|---|
| Clone ID: | RNL-4 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | NSP-C; Reticulon-1; Neuroendocrine-specific protein |
| Amount: | 100 μg |
| Application Codes Clone: | FC; IHC; WB; ELISA; IF |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for reticulon-1C. It recognizes an epitope located within the first 20 amino acids of Reticulon-1C (NSP-C). |
| Application Notes: | The specificity of the original format of the antibody for NSP-C was established in an ELISA assay. Immunofluorescence analysis of COS-1 cells, transfected with NSP-C cDNA, showed staining of the endoplasmic reticulum with the antibody. The antibody detected NSP-C by western blot analysis (Senden et al., 1996; PMID: 8900485). This antibody was used for immunohistochemistry for the detection of NSP-C on lung carcinoid, atypical carcinoid of the lung, SCLC and squamous cell carcinoma (Senden et al., 1997; PMID: 9227337). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |