Mfg Part Number
Ab03358-1.1

Vector Labs Ab03358-1.1 Anti-Lamin A [133A2], Mouse IgG1, kappa (100 μg)

Quick Overview
The original antibody was generated by immunizing a BALB/c mouse with partially purified recombinant human lamin A.
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Product Class:Purified
Clone ID:133A2
Synonyms:Prelamin-A/C; Lamin-A/C
Amount:100 μg
Application Codes Clone:FC; IHC; WB; IF
Shipping Temperature:Wet Ice
Buffer Composition:PBS with 0.02% Proclin 300.
Original Format:IgG3
Storage Temperature:Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Chimeric Use Statement:This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG3 format, for improved compatibility with existing reagents, assays and techniques.
Specificity Statement:The antibody recognizes an epitope located between residues 598-611 of lamin A.
Application Notes:The antibody detected lamin A by western blot analysis (Hozák et al., 1995; PMID: 7769007 and Broers et al., 1997; PMID: 9243284). The original format of the antibody strongly stained all tubular epithelium cells of kidney by immunohistochemistry (Broers et al., 1997; PMID: 9243284). The original antibody was used for staining of Sertoli cells, Leydig cells and Peritubular cells in normal testis and parenchyma adjacent to TGCT by immunohistochemistry (Machiels et al., 1997; PMID: 9274531). This antibody was used for detection of lamin A expressed on CHO-K1 cells by flow cytometry (Broers et al., 1999; PMID: 10504295). The original antibody was used to stain lamin A on late apoptotic cell (Broers et al., 2002; PMID: 12553668). The antibody detected laimin A in fibroblast cells by immunofluorescence analysis (van Tienen et al., 2019; PMID: 30420677).
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Brand Vector Labs
UNSPSC 12161500