Mfg Part Number
Ab03370-23.0
Vector Labs Ab03370-23.0 Anti-HLA-Cw6 [Cw6_4], Rabbit IgG, lambda (200 μg)
Quick Overview
The original antibody was isolated from fully synthetic human combinatorial antibody library (HuCAL) by screening against a cell-bound human lymphocyte antigen HLA-Cw6. Cw6 stable cell line was generated by transfecting human lymphoblastoid LCL 721.221 HLA class I null cell line.
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| Product Class: | Purified |
|---|---|
| Clone ID: | Cw6_4 |
| Synonyms: | HLA-C; HLAC; HLA-Cw; HLA class I histocompatibility antigen C alpha chain; Human leukocyte antigen C |
| Amount: | 200 μg |
| Application Codes Clone: | FC; IP |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Human scFv format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human HLA-Cw6. This antigen-presenting major histocompatibility complex class I (MHCI) molecule has an important role in reproduction and antiviral immunity. |
| Application Notes: | The binding specificity of the scFv antibody towards human HLA-Cw6, expressed on the cell surface was done using flow cytometry. This antibody was also used for the immunoprecipitation of Cw*0602-transfected LCL721.221 cells (WO2001014558). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |