Mfg Part Number
Ab03378-23.0
Vector Labs Ab03378-23.0 Anti-CD226 [DN9], Rabbit IgG, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing 4-6 weeks old female SPF or BALB/c mice with human DNAM-1 commercial antigen.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | DN9 |
| Synonyms: | DNAM1; DNAM-1; TLisA1; PTA-1; CD226 antigen; DNAX accessory molecule 1; T lineage specific activation antigen 1; platelet and T cell antigen 1 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human CD226. This protein is expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. It is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. It acts as cell surface receptor for NECTIN2. On binding with ligand it stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. |
| Application Notes: | The binding characterization of this antibody to human CD226 was done using ELISA. This antibody was used for the detection of CD226 expressed on Jurkat cells using flow cytometry (CN112940122). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |