Mfg Part Number
Ab03392-10.3
Vector Labs Ab03392-10.3 Anti-HER-2 [3A3], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing rabbits with Her-2.
$517.40
Order will ship within 1-3 business days
| Product Class: | Purified |
|---|---|
| Clone ID: | 3A3 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340; EP3 |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB; ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Rabbit IgG format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for Her-2. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis (affinity constant = 1.09 × 10^11M^-1). The antibody specifically detected HER-2 protein in Western blot analysis. The antibody 3A3 and the commercial antibody EP3 were used to stain breast cancer tissue. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 3A3 was higher than the commercial antibody. The antibody and the commercially available antibody EP3 were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN113621069A). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |