Mfg Part Number
Ab03400-10.0
Vector Labs Ab03400-10.0 Anti-MPO [12F3A4C11], Human IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing mice with MPO.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 12F3A4C11 |
| Synonyms: | CGMCC No. 19684; myeloperoxidase |
| Amount: | 200 μg |
| Application Codes Clone: | IHC; WB |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG2a |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for MPO. Myeloperoxidase (MP0) is a cationic glycoprotein with a relative molecular weight of 133-155kD and an isoelectric point of 1.0 secreted by neutrophils, macrophages and monocytes. MPO is part of the host defense system of polymorphonuclear leukocytes and it is responsible for microbicidal activity against a wide range of organisms. |
| Application Notes: | The antibody specifically detected MPO by Western blot analysis. The antibody 12F3A4C11 and a commercial rabbit polyclonal antibody were used to stain granulocytic sarcoma. Results showed the antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 12F3A4C11 was higher than the commercial antibody. The antibody and the commercially available antibody were simultaneously detected on the normal tissue chip, indicating that the specificity of the antibody in normal tissue was equivalent to that of the commercially available antibody (CN112194724B). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |