Mfg Part Number
Ab03408-23.0
Vector Labs Ab03408-23.0 Anti-HspB3 [7B4], Rabbit IgG, lambda (200 μg)
Quick Overview
The original antibody was generated by immunizing a barnevelder chicken with an antibody antigen cocktail comprising recombinant purified human antigens α-fodrin, hPop1, HspB3, Ro52, Rpp30, Rrp4 and Rrp42 in complete Freund's adjuvant. B cells that were harvested from the bone marrow and peripheral blood lymphocytes of immunized chickens was used to generate recombinant scFv phage display libraries. The specific clone was identified by panning the library against specific antigen.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 7B4 |
| Synonyms: | Heat shock protein beta-3; Heat shock 17 kDa protein; HSP 17; Protein 3 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | scFv |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Chicken scFv format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | The antibody is specific for HspB3. HspB3 is an inhibitor of actin polymerization and it promotes myogenesis by regulating the lamin B receptor. |
| Application Notes: | The specificity of the original format of the antibody was confirmed by ELISA analysis (Hof et al., 2008; PMID: 18062792). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |