Mfg Part Number
Ab03427-10.3
Vector Labs Ab03427-10.3 Anti-Glypican-1 [AbAb-GPC1], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing 6-week-old healthy New Zealand female white rabbits subcutaneously with human glypican-1.
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| Product Class: | Purified |
|---|---|
| Clone ID: | AbAb-GPC1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | GPC1 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Rabbit IgG format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human glypican-1, which is a cell surface proteoglycan that bears heparan sulfate. This protein is required for skeletal muscle differentiation. Glypican-1 (GPC1) was significantly expressed in serum exosomes of patients with pancreatic cancer and so GPC1 is considered as a tumor marker for pancreatic cancer. |
| Application Notes: | The binding characterization of this antibody to human glypican-1 was determined using ELISA. The binding of this antibody to human glypican-1 expressed on the surface of human breast cancer cell line MDA-MB-231 was determined using flow cytometry (CN112300283). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |