Mfg Part Number
Ab03432-10.0
Vector Labs Ab03432-10.0 Anti-TIM-3 [8E11], Human IgG1, kappa (200 μg)
Quick Overview
The original antibody was generated by immunizing 6-8 weeks old female BALB/c mice with recombinant human TIM-3 protein.
$517.40
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| Product Class: | Purified |
|---|---|
| Clone ID: | 8E11 |
| Synonyms: | CD366; HAVCR2; HAVcr-2; TIM3; TIMD-3; TIMD3; Hepatitis A virus cellular receptor 2; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; FC |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques. |
| Specificity Statement: | This antibody binds human TIM-3. Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein expressed on the cell surface of IFNγ producing CD4+ Th1 and CD8+ Tc1 cells. This protein is also expressed on the surface of Th17 cells, regulatory T-cells and innate immune cells like dendritic cells, NK cells and monocytes. It is a cell surface receptor implicated in modulating innate and adaptive immune responses. |
| Application Notes: | This antibody can be used in the detection of human TIM-3 using ELISA. The binding characterization of this antibody for human TIM-3 was done using indirect immunofluorescence labelling and flow cytometry (CN106632675). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |