Mfg Part Number
Ab03443-10.159
Vector Labs Ab03443-10.159 Anti-E2/E3E2 envelope protein [WD11F], Human IgG1-Fc Fusion, (100 μg)
Quick Overview
An immune phage display library derived from the peripheral blood lymphocytes of a llama that had been immunized with an equine vaccine that includes killed WEEV (West Nile Innovator + VEWT) was generated. The antibody was selected by panning the library against recombinant envelope (E2/E3E2) protein from WEEV.
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| Product Class: | Purified |
|---|---|
| Clone ID: | WD11F |
| Synonyms: | Western equine encephalitis virus |
| Amount: | 100 μg |
| Application Codes Clone: | SPR |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | VHH |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Chimeric Use Statement: | This chimeric human antibody was made using the variable domain sequences of the original VHH format, for improved compatibility with existing reagents, assays and techniques. |
| Specificity Statement: | The antibody is specific for E2/E3E2 envelope protein.Two envelope proteins, glycoproteins E1 and E2, associate as trimers of E1-E2 dimers on the viral surface, and make up 80 spikes on the viral surface. |
| Application Notes: | The binding affinity of the VHH fragment for the WEEV E3E2 recombinant protein was measured by surface plasmon resonance (Kd= 7.2 ×10^−9 M). The ability of the antibody to detect the recombinant protein in a MagPlex sandwich immunoassay was confirmed (Liu et al., 2018; PMID: 31544894). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |