Mfg Part Number
Ab03451-10.3
Vector Labs Ab03451-10.3 Anti-Der p 2.0103 [7A1], Human IgG1, Fc Silent™, kappa (200 μg)
Quick Overview
The original antibody was isolated from a combinatorial phage display library generated from a mite allergic patient.
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| Product Class: | Purified |
|---|---|
| Clone ID: | 7A1 |
| Heavy Chain Modification: | Fc Silent™ |
| Synonyms: | DERP2; Mite group 2 allergen Der p 2; Allergen Der p II; House dust mite; DPX; Der p 2 |
| Amount: | 200 μg |
| Application Codes Clone: | ELISA; inhibition; crystallography |
| Shipping Temperature: | Wet Ice |
| Buffer Composition: | PBS with 0.02% Proclin 300. |
| Original Format: | IgG1 |
| Storage Temperature: | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C. |
| Specificity Statement: | This antibody binds to an epitope on the Der p 2 which overlaps with the human IgE binding sites. The antibody recognized the six variants: Der p 2.0101, Der p 2.0102, Der p 2.0103, Der f 2.0101, Der f 2.0102, and Der f 2.0103. |
| Application Notes: | The crystal structure of Der p 2.0103–7A1Fab was determined. The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody was able to inhibit Der p 2.0103 (Glesner et al., 2019; PMID: 31554696). |
| Brand | Vector Labs |
|---|---|
| UNSPSC | 12161500 |